The study was conducted at Busitta village, Sironko district in Eastern Uganda to measure association between exposure to helminth and occurrence of helminthosis in goats in a randomized clinical trial in two age groups of goats, 8-12 weeks and 16-20 weeks old respectively, under the management of the goat farmers. The unexposed goats were given albendazole orally monthly while the exposed goats were given the placebo, a mixture of maize meal and water. The association between exposure to disease and disease (moderate gastro-intestinal infection) was detected by measures of association namely the relative Risk (RR), attributable risk (AR) and attributable fraction (AF). The RR showed that in both age groups there was association between exposure and helminthosis, and the risk was more in the younger goats. The AR showed that there was effect of exposure to helminth infection in both age groups. The AF which was calculated to reveal what proportion of the disease in the exposed group was due to helminth infection showed that the proportion of the disease in the exposed group due to helminth infection was higher in the younger goats.