Sprague dawely rats are widely used for in vivo evaluation of biomaterials. Here we reported highly prevalence of Strobilocercus (Cysticercus fasciolaris) cysts the intermediate bladder worms of the cat tape worms Taenia taeniaeformis, in the liver and body cavity of 71 out of 75 (94.66%) Sprague dawely male rats divided into 3 groups used for in vivo evaluation of denture material in our laboratory. Bladder worms induced fibrosarcoma in the liver and gastroenteropathy in the stomach and intestine. The bladder worm appeared as elongated and consisted of a series of segments. There were variations in the number and size of strobilocerci between infected rats. Liver sections revealed fibrosarcoma and infiltration of plasma cells, macrophages and eosinophils. Gastric mucosal hyperplasia, intestinal mucosal hyperplasia and proliferation of duodenal submucosa glands were observed also. The tape worm larva was confirmed as Strobilocercus fasciolaris by feeding 5 cats with infected liver and isolation of adult worms which revealed typical anterior rostellus, sucker and lack of neck. This is the first report about the heavily natural infection of Cysticercus fasciolaris with gastroenteropathy and liver fibrosarcoma between laboratory rats from experimental groups.
You may also start an advanced similarity search for this article.